Effect of vicarious discrimination on race-based stress symptoms among Asian American young adults during the COVID-19 pandemic.

OBJECTIVE: The COVID-19 pandemic has led to a rise in anti-Asian hate crimes in the United States. Previous work has established that experiencing racism increases one's dysfunctional anxiety and avoidance actions-key symptoms of race-based stress symptoms. However, the psychological impact of vicarious, or secondhand, discrimination (witnessing racism targeting one's own race group) remains less understood. METHOD: We tested the hypothesis that higher reported vicarious discrimination would be associated with higher levels of race-based stress symptoms reported by Asian American young adults (n = 135) during the pandemic using a cross-sectional analysis of the COVID-19 Adult Resilience Experiences Study (CARES). Starting in April 2020, CARES assessed sociodemographic characteristics and key psychometric scales in young adults through three waves of online surveys. RESULTS: Our multiple regression analysis showed vicarious discrimination significantly predicted race-based stress symptoms, even after controlling for direct discrimination (p < .01). This association remained significant after controlling for age, gender, subjective childhood family social status, and preexisting psychiatric disorders (p < .01). Our results demonstrate that regardless of the effect that direct discrimination might have on race-based stress symptoms, witnessing discrimination against members of one's own racial group is significantly associated with increased race-based stress symptoms (b = 2.68, p < .01). Social media was the most common source of vicarious discrimination, with one out of three participants in our sample reporting nearly daily exposure. CONCLUSION: Providers should intentionally create a space within the therapeutic setting to discuss the effects of vicarious discrimination. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

How do I save cell therapy product's storage space?

BACKGROUND: Availability of liquid nitrogen (LN2) freezer storage space is a major challenge for many transplant programs as they continue to grow and accumulate products. The recent trend of allogeneic grafts cryopreservation that started during the COVID-19 pandemic, made the situation even worse requiring an increase in storage capacity. Multi-compartment cryopreservation bags can help save storage space but can be tricky to use. Here, we describe the validation of muti-compartment cryopreservation bags for the purpose of donor lymphocyte infusion (DLI) aliquots. METHODS: We validated the use of five compartment cryobags for cryopreservation of cell therapy products. Four products were cryopreserved using these bags and each compartment was tested post-thaw for product volume distribution, total cell count recovery, and viability. Additionally, the integrity of both bag compartments and labels was assessed as well. RESULTS: All tested specimens met post-thaw viability and TNC recovery acceptability criteria. Fill volume was optimized at 24-25 mL for acceptable volume distribution between aliquots. With proper heat sealing between compartments, all aliquots retain their integrity and cryopreservation labels were adherent and legible. CONCLUSIONS: Muti-compartment bags can be used successfully for cryopreservation of cell therapy products and increase storage capacity.

Examining Coping and Resilience in People with Acquired Brain Injury During the Pandemic

Research Objectives To understand the relationship between use of coping skills and resilience in adults with an acquired brain injury (ABI) during the beginning of the Coronavirus Disease of 2019 (COVID-19) pandemic. Design Survey data was collected via online platform, Research Electronic Data Capture (REDCap). Setting The general community. Participants Participants as part of a convenience sample included self-identified adults with a traumatic brain injury (TBI) or stroke, 18 years or older (n = 99). Exclusion criteria were other neurological diagnoses or serious mental illnesses. Interventions Not applicable. Main Outcome Measures The outcome measures were the following: COVID-19 Experiences subsection of the COVID-19: Impact of the Pandemic and Health Related Quality of Life in Cancer Patients and Survivors Scale (Cov-PHRQoL) and the Brief Resilient Coping Scale. Results There was a significant group difference for race, (p = .04), with the Non-Coping Group having more people of minority status. The Coping Group reported a greater appreciation of family and friends (p= .001), greater appreciation for life (p= .001), more grateful for each day (p= .001), accepting of what they can't change (p= .001), and finding new ways to connect family and friends (p= .001). Compared to the Non-Coping Group, the Coping Group reported significantly greater resiliency and growth from a difficult situation (p = 0.006). Conclusions The COVID-19 pandemic provided a unique opportunity to examine the relationship between coping skills and resilience in people with ABI when faced with a novel stressor. People who utilized coping skills demonstrated positive outcomes in the form of perceived benefits and greater appreciation for who they had in their life. Furthermore, the Coping group was able to reframe difficult situations to find psychological growth. More research must be done to determine the relationship between coping skills and resilience in people with ABI, as well as what aspects of coping skills and resilience are most crucial to producing positive outcomes for people with ABI when faced with novel stressors. Author(s) Disclosures None.

Sequestration of Imaging Studies in MIDRC: A Multi-Institutional Data Commons

The Medical Imaging and Data Resource Center (MIDRC) is a multi-institutional effort to accelerate medical imaging machine intelligence research and create a publicly available image repository/commons as well as a sequestered database for performance evaluation and benchmarking of algorithms. After de-identification, approximately 80% of the medical images and associated meta-data will become part of the open repository and 20% will be sequestered and kept separate from the open commons. To ensure that both the public, open dataset and the sequestered dataset are representative of the population available, demographic characteristics across the two datasets must be balanced. Our method uses multidimensional stratified sampling where several demographic variables of interest are sequentially used to separate the data into individual strata, each representing a unique combination of variables. Within each stratum, patients are randomly assigned to the open set (80%) or the sequestered set (20%). Thus, for p variables of interest, the balance of the pdimensional distribution of variable combinations can be controlled. This algorithm was used on an example COVID-19 dataset containing image exams of 4662 patients using the variables of race, age, sex at birth, and ethnicity, each containing 8, 8, 2, and 4 categories, respectively. After stratification of this dataset into the two subsets, resulting distributions of each variable matched the distribution from the original dataset with a maximum percent difference from its original fraction of 0.4%. These results demonstrate that the implemented process of multi-dimensional sequential stratified sampling can partition a large database while maintaining balance across several variables. © 2022 SPIE. All rights reserved.

Application of the ICF and OTPF-4 to Conceptualize the Dual Diagnosis of COVID-19 and Stroke: Implications for Occupational Therapy Practice in Acute and Inpatient Rehabilitation.

There is mounting evidence that the vascular manifestations associated with COVID-19 are linked to ischemic strokes. The emergence of patients with both COVID-19 and cerebrovascular accidents (COV-CVA) has created a need to adjust occupational therapy service delivery for inpatients with this dual diagnosis. This clinical perspective paper conceptualizes COV-CVA as a health condition using the International Classification of Functioning, Disability and Health Framework (ICF). The Occupational Therapy Practice Framework-4 was used to guide clinical considerations and recommendations for the evaluation, intervention, and discharge planning of patients with COV-CVA.

Collaborative autoethnography in examining online teaching during the pandemic: from a ‘teacher agency’ perspective

The COVID-19 pandemic outbreak forced universities to immediately shift to online teaching, and the transition presented unprecedented challenges. This paper reports our findings from a collaborative autoethnography study with a special focus on the challenges we encountered and our agentive responses in teaching online. Data reveal four major challenges (1) unpredictable situations, (2) shifting teacher roles in online context, (3) issues on course design, expectations, grading, and feedback, and (4) technology issues. Also, we reported four agentive responses (1) adopting a positive attitude, (2) reexamining our teaching practices and educational goals, (3) exploring alternative pedagogical approaches, and (4) strategically implementing technology to enhance teaching and learning. These intentional reflections became opportunities for us to revisit our positionality, analyze our teaching experiences, and transform them into tools in supporting students. This study calls for more resources for professional development, as well as further conversations and collaborations among teachers and researchers. [ FROM AUTHOR] Copyright of Teaching in Higher Education is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

Stroke Recovery During the COVID-19 Pandemic: A Position Paper on Recommendations for Rehabilitation.

Health care delivery shifted and adapted with the COVID-19 pandemic caused by the novel severe acute respiratory syndrome coronavirus 2. Stroke care was negatively affected across the care continuum and may lead to poor community living outcomes in those who survived a stroke during the ongoing pandemic. For instance, delays in seeking care, changes in length of stays, and shifts in discharge patterns were observed during the pandemic. Those seeking care were younger and had more severe neurologic effects from stroke. Increased strain was placed on caregivers and public health efforts, and community-wide lockdowns, albeit necessary to reduce the spread of COVID-19, had detrimental effects on treatment and recommendations to support community living outcomes. The American Congress of Rehabilitation Medicine Stroke Interdisciplinary Special Interest Group Health and Wellness Task Force convened to (1) discuss international experiences in stroke care and rehabilitation and (2) review recently published literature on stroke care and outcomes during the pandemic. Based on the findings in the literature, the task force proposes recommendations and interdisciplinary approaches at the (1) institutional and societal level; (2) health care delivery level; and (3) individual and interpersonal level spanning across the care continuum and into the community.

The impact of the COVID-19 pandemic on engagement in activities of daily living in persons with acquired brain injury.

PRIMARY OBJECTIVES: This study examined (a) the impact of coronavirus disease-2019 (COVID-19) pandemic on engagement in activity participation in persons with acquired brain injury (ABI); and (b) whether changes in activity participation during the pandemic were associated participants' health-related quality of life (HRQoL). RESEARCH DESIGN: Exploratory online survey study. METHODS: Eighty-seven respondents with ABI and 98 healthy adults (HA) participated in this study. Engagement in activity participation during COVID-19 was calculated as a percentage of the activities participants performed before the pandemic. MAIN RESULTS: Participants with ABI modified their activities less than HA in order to maintain level of engagement in activity participation. They stopped performing more activities during the pandemic compared to HA and compared to their pre-pandemic engagement. Both groups continued to do similar percentage of activities without modifications compared to before the pandemic. Better HRQoL in both groups was predicted by a larger percentage of activities continued and fewer activities stopped. CONCLUSION: Results emphasize the importance of addressing activity participation changes during situations where there are disruptions of the individual's habits and routines in order to minimize negative consequences of such changes.

Relationships between changes in daily occupations and health-related quality of life in persons with multiple sclerosis during the COVID-19 pandemic.

BACKGROUND: The COVID-19 pandemic provided a unique opportunity to explore the impact of the mandated lockdown and social distancing policies on engagement in daily occupations for individuals with multiple sclerosis (MS) and able bodied (i.e. healthy) adults. The study also examined whether the changes in daily occupations were associated with health-related quality of life (HrQOL). METHODS: Between the spring and early fall of 2020, 69 persons with MS and 95 healthy adults completed an online survey that included measurements of 26 activities of daily life. For each activity, participants reported whether they continued to perform the activity (with or without adjustments), whether they stopped, or started to perform the activity during the pandemic. Social support, HrQOL, and demographics, including financial distress were also obtained. RESULTS: Participants with MS and healthy adults both reduced the number of activities performed during the pandemic. Healthy adults continued to do more activities with and without adjustments compared with participants with MS. In both groups, better HrQOL was associated with the number of activities participants continued to do with and without adjustments, and worse HrQOL with the number of activities they stopped doing. CONCLUSIONS: Fewer persons with MS engaged in everyday occupations than healthy adults following the COVID-19 pandemic. The ability to maintain occupational engagement and to participate in social and daily activities is important for maintaining high HrQOL in both groups. Thus, these results call for attention in treatment and self-management of MS symptomatology.

Fighting two pandemics at once: When COVID-19 meets racism

The Centers for Disease Control also suggest that racial/ethnic disparities in living and working conditions during the pandemic have led to increased health risks for these racial/ethnic minorities. The self-determination theory includes the need for autonomy as one of the most important human needs to be fulfilled in order to ensure intrinsic motivation on the job (Deci & Ryan, 2000). [...]under stressful situations, lacking control can influence the likelihood of counterproductive work behavior (Tucker etal., 2009). In the United States, because of the stigma associated with COVID-19, the two million small businesses owned by Asians are at particular risk of losing customers (Kwon, 2020). Since the U.S. declared a national emergency on March 13, Asian-owned businesses saw a 60% decrease in revenue (JP Morgan Chase and Company, 2020). [...]although the COVID-19 pandemic may be contained one day, its influence on workers and organizations can be long lasting.

When Perceptions Are Fragile But Also Enduring: An Asian American Reflection on COVID-19

With the increasing death tolls and economic downfall, COVID-19 has also unearthed anti-Asian racism and xenophobia in the United States and globally. In this article, we examine how the current anti-Asian sentiments are not new occurrences risen with COVID-19. Instead, the perceptions about people of Asian descent as foreign threats have become more visible due to the pandemic. As we grapple with and heal from the traumas of COVID-19, there is a great need to acknowledge not only the shared humanity and interconnectedness among people but also to note the legacies of racialization and inequity that affect the experiences of the current pandemic that are lived differently.